The Black Nebula Empire attacks Earth and threatens to blow up the planet with a bomb they placed on Earth if counter attacked. Earths hopes rest on the Yamato crew as they go to the Black Nebula Planet and try to find a way to defuse the bomb before it's too late.

Source: ANN

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Sequel: Uchuu Senkan Yamato 3
Prequel: Uchuu Senkan Yamato: Aratanaru Tabidachi
Alternative version: Yamato yo Towa ni: Rebel 3199