Atom is created by Dr. Tenma as a replacement for his human son Tobio following the boy's death in a car accident. Despite his best of intentions, Tenma soon becomes frustrated that Atom never grows any taller and continues to make mistakes as he learns to harness his robot powers. In a moment of mental weakness, Tenma sells Atom to the owner of the Robot Circus, but is soon rescued by the newly appointed head of the Ministry of Science, the kindly Dr. Ochanomizu.

In the adventures to come, Atom proves himself time and again, helping with rogue robots, desperate criminals, missions to other planets and even finding time to attend school.

Along the way he is helped by his teacher, Shunsaku "Higeoyaji" Ban, his friends, his sister Uran and the rest of his robot family.

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Alternative version: Tetsuwan Atom (2003)
Alternative version: Tetsuwan Atom (1980)
Same characters: Jungle Taitei
Other: Tetsuwan Atom: Shinsengumi
Other: Tetsuwan Atom: Uchuu no Yuusha
Same setting: Jetter Mars
Alternative setting: Hyakumannen Chikyuu no Tabi Bander Book
Same characters: Fumoon
Same setting: Akuma Tou no Prince: Mitsume ga Tooru
Same characters: Ravex in Tezuka World
Other: Tezuka Osamu ga Kieta?! 20 Seiki Saigo no Kaijiken
Prequel: Atom: The Beginning
Alternative version: Pluto
Other: Tetsuwan Atom (Shinsaku)