* Based on a card- and video-game franchise developed by Bushiroad, featuring a moe team of loli detectives.

Milky Holmes is a detective team composed of four girls who descended from famous detectives and possess supernatural powers known as "Toys". In this alternative world, instead of losing their Toys and becoming worthless students, they are on the path to becoming successful detectives. Under the guidance of Kobayashi Opera, they work to solve mysteries.

Note: The first episode received an early screening at a special event on August 18, 2012, at Shinjuku Wald 9 in Tokyo, which was streamed on Nico Nico Live on August 19, 2012. The regular TV broadcast took place on August 25, 2012. Additionally, the second episode received an early screening at a special event on December 9, 2012, at the Kawaguchi Cultural Center "Lillia Hall" in Saitama Prefecture. The regular TV broadcast took place during the Bushimo Oomisoka Anime Matsuri program on December 31, 2012.

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Alternative version: Tantei Opera Milky Holmes Dai 2 Maku