Sasami has always been special... but now she has been imbibed with a healthy dose of magic — which she plans to use to right the things wrong with the Earth, and, of course, help keep her brother Tenchi out of trouble. Naturally, there is going to be trouble: this time, it is the mysterious Pixy Misa... and Ryouko going at it against Aeka (as usual). Obviously all this is not making things any easier for Sasami.

Source: AnimeNfo

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Alternative version: Mahou Shoujo Pretty Sammy (1996)
Prequel: Tenchi Muyou! Bangaihen: Galaxy Police Mihoshi Space Adventure