Mikami Reiko runs a business known as GS (Ghost Sweeper) Mikami, where she exorcises any evil that is bothering people. Her assistant, Tadao, only works for Reiko to see her nude one day. Too bad he isn't getting paid much for his job anyway. Later, Reiko and Tadao meet a spirit named Oniku who comes to help them in solving the mysteries of the supernatural.

Source: AnimeNfo

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Side story: Ghost Sweeper Mikami: Gokuraku Daisakusen!!