Kei and Yuri are Trouble Consultants for the World Welfare Work Association (3WA) — codenamed the Lovely Angels or better known as the Dirty Pair. Even though they are quite efficient at getting results, their methods usually lead to excessive collateral damage, bringing tears to Chief Gooley's eyes, and grief to those unlucky enough to be helped by the Dirty Pair.

Kei's day begins with having to work through a mountain of paperwork, while Yuri visits Dr. Kubellstein to receive his latest laser ring invention. Chief Gooley sends them off to the lifers-only Karosu Prison built on a waste star, that has been taken over by the prisoners. Their task: bring back warden Shochou alive...

On Halloween night the Dirty Pair have been put on duty to catch a troublemaker selling state secrets. A crash landing, and the escape of the secret cargo, a tactical robot weapon, certainly infuriates Chief Gooley. But the retrieval ends up being complicated since the robot is quite nimble on his feet and other criminal elements have picked this night to create chaos in Eleanor City...

On an agricultural planet, the recently ordained deity started killing believers. The Dirty Pair is sent in to investigate the irregularities at New Heaven...

— written by foo2

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Sequel: Dirty Pair: Project EDEN
Side story: Dirty Pair: Bouryaku no 005-bin
Prequel: Dirty Pair: Lovely Angels yori Ai o Komete