Those who have the blood of the Karasu Tengu (Crow Goblin) in their veins must forever fight against the powers of darkness. Along with four other holy ninja warriors Genbu (Black Snaky Tortoise), Suzaku (Red Phoenix), Seiryu (Blue Dragon), Byakko (White Tiger), Karasu Tengu Kabuto fights against the evil god Kuroyasha (Black Night Demon) Douki and his underlings such as Junin-shu (Top Ten Warriors).
Their battle continues through generations...

Source: Wikipedia

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Side story: Karasu Tengu Kabuto: Ougon no Me no Kemono