Ungrar, the King of Viruses, has escaped from his prison cell on Vaccine World. Maya, the Goddess of Vaccine World sends Mugimaru down to Earth to find a human to accept the powers of Vaccine World and become Magical Nurse. He finds the best (and the only willing) person for the job when he meets Nakahara Komugi.

Komugi is a playful, lazy, and easily distracted (typical) teenager whose dream is to become a cosplay idol. Balancing her career with the Kiri-Pro Promotion Company and her new job battling Ungrar's loyal henchman, the Magical Maid Koyori, Komugi is in for tumultuous times...

Source: ANN

Note: While the first volume had a DVD release date of 23.08.2002, it was initially aired on TV Kanagawa after midnight on 04.08.2002. The subsequent episodes also aired on TV Kanagawa some days prior to their DVD release.

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Same characters: The SoulTaker
Sequel: Nurse Witch Komugi-chan Magikarte Z
Other: Nurse Witch Komugi-chan R